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Computational Structural Biologist

Job LocationNantgarw
EducationNot Mentioned
Salary£35,000 - £45,000 per annum
IndustryNot Mentioned
Functional AreaNot Mentioned
Job TypePermanent, full-time

Job Description

Computational Structural BiologistCardiffShare Options Profectus have partnered with a MedTech company based in Cardiff who are developing a cutting-edge, leading medical discovery platform. By leveraging machine learning, they are able to predict antigen binding antibodies targets with high affinity.The client requires an experiencedComputationalStructural Biologistwho is anexpert in protein structures, who understands PDB data (including its biases) and protein-protein interactions (ideally antibody-antigen interactions), and can-do structural modelling, molecular docking, energy/binding calculations, and molecular dynamics simulations on proteins. The client is very interested in people who can (or could in working withthem) scale up these processes to a high throughput.My client is absolutely working towards commercialisation, but many of the problems are new and different from whats out there, so theyll really value people who can work creatively by drawing analogies to existing works, and iterate quickly in setting up, justifying and testing hypotheses.Key Requirements:

  • PhD. in Computer Science, Computational Biology, Immunology, or a related field (MSc will be considered with industry experience)
  • Strong knowledge ofprotein structures
  • Experienced in analysing antibody-antigen interactions
  • Experienced in structural modelling
  • Experience in molecular docking
  • Energy/binding calculations
  • Experience with molecular dynamics simulations on proteins
  • Understanding of PDB Data
  • Desirable Experience:
  • GCP and AWS knowledge
  • Antibody-specific experience
  • Machine learning
  • Drug discovery experience
  • Statistical expertise
  • As mentioned above, if you have experience with proteins, protein structures, antibody and antigen interactions, structural modelling, molecular docking and molecular dynamics on protein structures then I would definitely like to hear from you! Any candidate who has previously worked in Computational Biology and doesn’t match up perfectly, then still do get in touch.For more information about this role, the company and benefits, please get in touch on the details listed or hit apply if you have the relevant experience for immediate consideration. Required skills
  • Biology
  • Structural Modelling
  • Molecular Docking
  • Protein Structures
  • Protein Docking
  • Keyskills :
    Biology Structural Modelling Molecular Docking Protein Structures Protein Docking

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