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Senior Cheminformatician

Job LocationCambridge
EducationNot Mentioned
SalarySalary negotiable
IndustryNot Mentioned
Functional AreaNot Mentioned
Job TypePermanent , full-time

Job Description

CK Group are exclusively working with a global biopharmaceutical company and recruiting for an experienced Senior Cheminformatician. The successful candidate will be part of a growing Computational Chemistry team. This role will be based at their sitein Cambridge on a permanent basis with flexibility of hybrid working. The Company:Our client is a fully integrated biopharmaceutical company focused on bringing life-changing medicines to patients globally who are working to generate and advance a broad and deep pipeline of novel medicines across multiple therapeutic areas, including neurology,immunology, gastroenterology and inflammatory diseases.The Role:Fantastic opportunity to join an expanding team that are actively involved in multiple drug discovery projects, AI and structure-based drug discovery (SBDD) collaborations. Using the state-of-the-art CADD techniques, you will support and drive discovery projectsfrom early stage to clinical candidate stage working closely with cross-functional teams (chemistry, pharmacology and structural biology). Responsibilities:

  • Contribute to multidisciplinary GPCR SBDD projects by applying a broad set of computational chemistry and cheminformatics approaches
  • Develop customised computational chemistry and cheminformatics tools and workflows to extract, integrate and analyse complex chemical, structural, pharmacological and ADMET data within the context of SBDD.
  • Play an active role in new initiatives, such as: Development of new computational chemistry CADD software via external collaborations; Structural bioinformatics and StaR data driven GPCR protein engineering and GPCR-customised library design
Your Background:
  • PhD. or equivalent experience in computational chemistry, cheminformatics, or a related discipline
  • Experience using cheminformatics toolkits or computational chemistry tools to solve problems such as similarity searching, clustering, QSAR modelling and virtual library enumeration
  • Strong coding skills in Python and familiarity with common data science packages
  • Experience in AI approaches such as Deep Generative Models
  • Computational chemistry experience within a collaborative multi-disciplinary medicinal chemistry research environment
  • Background in molecular recognition and the structural and physicochemical property determinants of small molecule binding to proteins
Benefits:Discretionary bonuses25 days holiday plus bank holidays plus the option to purchase an additional 5 days each yearShare optionsPensionHealth (inc family) and wellbeing benefits including a subsidised individual gym membership. Apply:It is essential that applicants hold entitlement to work in the UK. Please quote job reference 56268 in all correspondence.

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