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Senior Bioinformatician

Marketplace Group
Job LocationNewcastle Upon Tyne
EducationNot Mentioned
SalaryCompetitive salary
IndustryNot Mentioned
Functional AreaNot Mentioned
Job TypePermanent, full-time

Job Description

Leading Medical Devices organisation requires a Senior Bioinformatician, the successful candidate will work within the Assay Team to develop point of care molecular diagnostic assays and associated technologies. It is an opportunity for candidates with a strong background in sequence-based bioinformatics to take a key role on projects leading to the development of the platform and diagnostic assays.About the role:This role requires an experienced bioinformatician to support the Group commercialisation program by working within the Assay Team to support the development of assays for the Companys diagnostic platform.A key success factor for this position is the ability to work in a fast paced, cross functional group environment, with a willingness to be involved across a wide area of responsibilities. A great capacity and desire for taking on new responsibilities and challenges is essential as the company grows and projects expand.The successful candidate will be responsible for supporting the development of in-vitro diagnostic (IVD) products in the areas of nucleic acid testing.Duties may include:

  • Work within the Assay Team to deliver molecular diagnostic product pipeline
  • Collate and annotate reference sequences across multiple microorganisms
  • Create and implement new custom tools to store and interpret sequence data
  • Interrogate sequence data and design new diagnostic assays.
  • Work towards the goals of collaborative projects with external partners and be point of contact for some.
  • Generate, record and present complex data, to line manager, colleagues, senior management and external partners.
  • Attend lab, team and project meetings and present and report findings
  • Write scientific plans and reports, SOPs, Risk assessments.
  • Manipulate and analyses datasets.
  • Keep up to date with the literature on point of care diagnostics, assay design, infectious disease diagnostics and other relevant areas.
  • Work within the quality systems following GDP and working to ISO 13485 standard.
    • Skills and experience:
  • BSc/MSc degree or equivalent in a relevant subject (i.e. bioinformatics, biology, computational science)
  • PhD in a relevant subject (i.e. bioinformatics, genomics) or previous work experience in a relevant technical, scientific role
  • Experience in bioinformatic analysis of sequencing data
  • Relevant experience in bioinformatics with a strong preference for microbial genomics experience
  • Familiarity with sequencing data (Sanger and NGS) and standard bioinformatics tools (alignment, variant calling, assembly etc.)
  • Experience in data manipulation and analysis of large genomic datasets
  • Knowledge and competence in R and other programming languages
  • Experience of sequence database development and management
  • Experience in nucleic acid amplification-based assay design and development
  • Knowledge of nucleic acid amplification and detection chemistries
  • Knowledge of statistics
  • Ability to work to the Companys Quality Systems and Policies in line with ISO13485 standards
  • Excellent work ethic and strong communication skills.
  • Good sense of humour and ability to work in a changing environment on complex projects.
  • Be eligible to work full time in the UK without restriction.
  • Several years experience in relevant areas such as bioinformatic support of assay development, diagnostics, and technology development.
  • Previous experience in the design and development of diagnostic devices
  • Demonstrated ability to lead collaborative projects with external partners
  • Previous experience in an industry or start-up setting
  • Previous experience in the validation and verification of molecular diagnostic assays
  • Hands on experience with the manipulation and development of PCR chemistries for diagnostic tests
  • Knowledge of infectious diseases and their diagnosis
    • Required skills
  • Bioinformatics
  • ISO13485

    • Keyskills :
    Bioinfmatics ISO13485

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