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Research Scientist

Marketplace Group
Job LocationNewcastle Upon Tyne
EducationNot Mentioned
SalarySalary negotiable
IndustryNot Mentioned
Functional AreaNot Mentioned
Job TypePermanent, full-time

Job Description

Leading Medical Devices Organisation requires an Assay Development Research Scientist.About the role:The successful candidate will work within the Assay Development Team to develop point of care molecular diagnostic assays and associated technologies. It is an opportunity for candidates with a strong background in molecular biology/diagnostics to take a key role on projects leading to the development of the platform and diagnostic assays. This role requires an Assay Research Scientist to support the company program by working within the Assay team to develop the Companys diagnostic platform.Duties may include:

  • Run, test and develop microfluidic diagnostic platforms
  • Lead the development and testing of new DNA amplification and detection technology
  • Design, develop and test new PCR based diagnostic assays
  • Undertake performance analysis and validation of assays
  • Work towards the goals of collaborative projects with external partners and be point of contact for some.
  • Generate, record and present complex data, to line manager, colleagues, senior management and external partners.
  • Attend lab, team and project meetings and present and report findings
  • Write scientific plans and reports, SOPs, Risk assessments, COSHH forms.
  • Manipulate and analyses datasets.
  • Keep up to date with the literature on Point of care diagnostics, rapid PCR, infectious disease diagnostics and other relevant areas.
  • Contribute to maintenance of the lab and equipment
    • Skills and experience:
  • A minimum of PhD in life sciences or equivalent experience in a non-academic setting
  • Experience in the design and development and testing of diagnostic assays
  • Detailed knowledge of nucleic acid amplification and detection chemistries, including significant hands on experience with qPCR
  • Significant wet lab experience covering general molecular techniques
  • Proven ability to take a leading role on multidisciplinary projects and ability to interact with external partners on fast paced projects
  • Ability to work to the Companys Quality Systems and Policies in line with ISO13485 standards
  • Be eligible to work full time in the UK without restriction
  • Excellent work ethic and strong communication skills.
  • Knowledge of bioinformatics, statistics and data analysis including R, manipulation of sequence data, analysis of assay performance
  • Previous experience in the design and development of diagnostic devices
  • Demonstrated ability to lead collaborative projects with external partners
  • Previous experience in the validation and verification of molecular diagnostic assays
  • Knowledge and experience of microfluidics
  • Experience with the manipulation and development of PCR chemistries for diagnostic tests
  • Experience with the stabilization of PCR chemistry (eg lyophilisation)
  • Knowledge of infectious diseases and their diagnosis.
  • Experience of product development
  • Knowledge and experience with fluorescence imaging and optics
  • Knowledge of software languages eg Pearl, Python
    • Required skills
  • Assay Development
  • ISO13485

    • Keyskills :
    Assay Development ISO13485

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