Associate Bioinformatician

Job Description

Exciting Medical Devices Development company seeks an Associate Bioinformatician.About the role.The successful candidate will work within the Assay Team to develop point of care molecular diagnostic assays and associated technologies. It is an opportunity for candidates with background in bioinformatics to contribute on projects leading to the developmentof diagnostic assays.The role requires an Associate bioinformatician to support the senior Bioinformatician in general tasks such as; software development, database maintenance and report generation.Work with the Group commercialisation program by working within the Assay Team to design assays for the Companys diagnostic platform.Duties may include:

• Work within the Assay Team to deliver molecular diagnostic product pipeline.
• Attend regular lab meetings.
• Be familiar with public reference sources such as GISAID and NCBI databases.
• Be familiar with NextGen sequencing and associated pipelines.
• Collate and annotate reference sequences across multiple microorganisms.
• Be confident using python and Jupyter Lab books as a working and application development environment along with GIT as a version control system.
• Generate, record, manipulate, analyse and present complex data to line manager, colleagues, senior management and external partners.
• Assist in report writing and generation of SOPs.
• Maintain records, logs and or databases of analyses for regulatory reporting purposes.
• Undertake periodic in silico review of existing assay designs to confirm ongoing suitability of the assay for VOC, VUI and variants being monitored.
• Work on collaborative projects with external partners and be point of contact for bioinformatics.
• Keep up to date with the literature on point of care diagnostics, assay design, infectious disease diagnostics and other relevant areas.
• Work within the quality systems following GDP and ISO 13485 standards.

Skills and experience:

• MSc degree or equivalent in a relevant subject (i.e. bioinformatics, computer science or statistics).
• Relevant experience in bioinformatics with a strong knowledge of microbial genomics .
• Familiarity with sequencing data (Sanger and NGS) and standard bioinformatics tools (alignment, variant calling, assembly etc.)
• Experience in data manipulation and analysis of large genomic datasets.
• Knowledge and competence in Python, Docker, Git, Linux, MySQL or similar software development tool.
• Knowledge of nucleic acid amplification and detection chemistries.
• Knowledge of statistics.
• Ability to work to the Quality Management Systems in line with ISO13485 standards.
• Excellent work ethic and strong communication skills.
• Ability to work in a changing environment on complex projects.

About the role.The successful candidate will work within the Assay Team to develop point of care molecular diagnostic assays and associated technologies. It is an opportunity for candidates with background in bioinformatics to contribute on projects leading to the developmentof diagnostic assays.The role requires an Associate bioinformatician to support the senior Bioinformatician in general tasks such as; software development, database maintenance and report generation.Work with the Group commercialisation program by working within the Assay Team to design assays for the Companys diagnostic platform.Duties may include:

• Work within the Assay Team to deliver molecular diagnostic product pipeline.
• Attend regular lab meetings.
• Be familiar with public reference sources such as GISAID and NCBI databases.
• Be familiar with NextGen sequencing and associated pipelines.
• Collate and annotate reference sequences across multiple microorganisms.
• Be confident using python and Jupyter Lab books as a working and application development environment along with GIT as a version control system.
• Generate, record, manipulate, analyse and present complex data to line manager, colleagues, senior management and external partners.
• Assist in report writing and generation of SOPs.
• Maintain records, logs and or databases of analyses for regulatory reporting purposes.
• Undertake periodic in silico review of existing assay designs to confirm ongoing suitability of the assay for VOC, VUI and variants being monitored.
• Work on collaborative projects with external partners and be point of contact for bioinformatics.
• Keep up to date with the literature on point of care diagnostics, assay design, infectious disease diagnostics and other relevant areas.
• Work within the quality systems following GDP and ISO 13485 standards.

Skills and experience:

• MSc degree or equivalent in a relevant subject (i.e. bioinformatics, computer science or statistics).
• Relevant experience in bioinformatics with a strong knowledge of microbial genomics .
• Familiarity with sequencing data (Sanger and NGS) and standard bioinformatics tools (alignment, variant calling, assembly etc.)
• Experience in data manipulation and analysis of large genomic datasets.
• Knowledge and competence in Python, Docker, Git, Linux, MySQL or similar software development tool.
• Knowledge of nucleic acid amplification and detection chemistries.
• Knowledge of statistics.
• Ability to work to the Quality Management Systems in line with ISO13485 standards.
• Excellent work ethic and strong communication skills.
• Ability to work in a changing environment on complex projects.

Keyskills :
BioinformaticsISO13485Assay