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Senior Scientist Analytical Development Project Lead

Job LocationMacclesfield
EducationNot Mentioned
SalaryCompetitive salary
IndustryNot Mentioned
Functional AreaNot Mentioned
Job TypePermanent, full-time

Job Description

Senior Scientist - Analytical Development Project Lead Macclesfield, Cheshire, UK At AstraZeneca, we are united by a common purpose: to push the boundaries of science to deliver life-changing medicines. Every single day, we make a difference by delivering potentially life-changing medicines to millions of people globally and by leading breakthrough science that promises to transform the treatment of disease. Our purpose is ambitious and so is our approach. Becoming a more agile and creative company means building a dynamic, inspiring culture where we celebrate diverse, bold thinking and act with a sense of urgency. We are curious, creative, and open to new ideas and ways of working.We work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity, even in the most difficult Situations because we are committed to doing the right thing. We believe in the potential of our people and you’ll develop beyond what you thought possible! We make the most of your skills and passion by actively supporting you to see what you can achieve no matter where you start with us.We are currently looking for lead analytical pharmaceutical development scientists in chemical development with scientific project-based experience. Join one of our Chemical Development teams within Pharmaceutical Technology and Development (PT&D), at our Macclesfield Campus, UK.Pharmaceutical Technology and Development (PT&D) are the bridge, which turns forward-thinking science into actual medicines that help millions of people. We work across the entire value chain, designing and delivering active ingredients, formulations and devices required to support new medicines – from supplies for use in early toxicology studies and clinical trials to developing the technology to ensure drugs can be scaled up for commercial manufacture.You will join a vibrant team that is working on the next generation of medicines and play a key role in the analytical development of new medicinal products. We will rely on you to bring a strong analytical perspective to multi-disciplinary project teams and to help lead the early and late stage development of drug substances. You will be responsible for using science and innovation to deliver analytical knowledge that encompasses understanding of manufacturing processes, control strategy and robustness. We would like you to work independently and to lead interactions within cross functional teams, including with Process Chemists, Engineers, Contract Manufacturing Organisations (CMOs), Product Development, Regulatory CMC, Quality Assurance and Supply Chain.As part of a global company with a focus on developing its people, you will have the opportunity to develop both personally and professionally while helping to deliver medicines that help millions of patients worldwide. Main Duties and Responsibilities:

  • Leading API analytical activities to support project progression from clinical development phases through to late development and commercialisation
  • Developing API analytical control strategies, keeping a strong focus on quality for our patients
  • Identifying and solving potential analytical project issues
  • Planning and conducting lab-based experimental work in accordance with project timelines
  • Supporting the technical development of other scientists
  • Collaborating with internal and external manufacturing partners to deliver the analytical aspects of GMP API manufacture
  • Keeping abreast of scientific developments and proactively applying existing and novel approaches to projects
  • Authoring the CMC components of regulatory submissions and preparation of successful regulatory responses
  • Required Qualifications, Skills, Knowledge and Experience:
  • A degree (BSc, MSc or equivalent) in Chemistry or Analytical Chemistry with a proven track record of analytical development in a pharmaceutical environment, or a PhD including aspects of analytical measurement
  • Knowledge and practical experience across a range of analytical techniques, e.g. LC, MS, GC, NMR
  • Scientific leadership skills and the ability to use knowledge and experience to assess options available and deliver robust scientific contributions to projects
  • Strong problem-solving skills, underpinned by strong practical laboratory experience
  • Experience of working collaboratively within a mixed skill technical team, and ability to develop and utilise networks
  • Ability to communicate complex scientific information in a clear, concise and understandable way
  • Desirable Skills, Knowledge and Experience:
  • Ability to confidently and successfully lead improvement projects
  • Strong influencing, planning and prioritisation skills to ensure project delivery to deadlines
  • Experience of leading technical teams, coaching and people development
  • Commitment to improvement and innovation and knowledge of Lean principles
  • Knowledge and practical experience of quality and regulatory requirements (GMP and ICH) and health and safety requirements
  • Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering ground-breaking methods and bringing unexpected teams together. Interested Come and join our journey!How to ApplyTo be considered for this exciting opportunity, please complete the full application form on our website. Please include your CV and a covering letter, to present your motivation for applying, and suitability for the role.AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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