Fluorescence Assay Development Researcher - Cambs

Job Description

My clients in Cambridgeshire are looking for a Fluorescence Assay Development Researcher. This role is commutable from Cambridge, Bedford, St. Neots, Huntingdon, Sandy, Yaxley.JOB PURPOSE:To accelerate the development of the companys novel fluorescent tags by evaluating their suitability and performance in a range of biological applications. You will be working as part of an interdisciplinary team that includes chemists, physicists and biochemists.KEY RESULT AREAS: Develop and optimise biochemical and biophysical assays to evaluate the suitability of novel bio-functionalised fluorescent nanoparticles for end-use applications. Support the synthesis team in material development of fluorescent nanoparticles by carrying out routine assay work using established protocols. Effective communication with all team members and the wider organisation to distribute results, discuss problems, and provide next-step recommendations to progress the project. Accurate recording of all practical work to ensure that new Intellectual Property (IP) is appropriately documented.MAIN ACTIVITIES: Develop and optimise assays to evaluate the suitability of bio-functionalised nanoparticles for end-use applications, critically analysing and reporting results, identifying trends and anomalies. Support the synthesis team in material development of novel fluorescent nanoparticles by carrying out assay work using established protocols, providing timely feedback on performance. Assist in identifying and contacting external experts to accelerate progress and evaluate new proposals. Initiation, delivery and documentation of high-quality studies and mini projects based on sound scientific hypotheses to achieve R&D targets. Compilation of results in a timely and accurate manner, in the required format (written, verbal, formal presentation). Presentation of data in one-to-one discussions, team meetings and at wider discussion forums. Creative contribution to brainstorms, studies and project meeting discussions. Effective communication with biologists, chemists, physicists, and project leaders, as well as external collaborators. Identification of IP, filing of invention disclosures, and providing feedback to ensure high quality patent applications. Where required, assist with market analyses to evaluate unmet needs and potential value propositions.KNOWLEDGE/EXPERIENCE/SKILLS REQUIRED: A PhD in a relevant biological discipline or alternatively a degree within a relevant biological discipline coupled with equivalent relevant experience in an industrial or academic environment. Extensive experience within at least one of the following areas is essential:o Fluorescence-based assay development and optimisation for the detection of proteins or nucleic acids.o Surface chemistry strategies for immobilisation of proteins and nucleic acids to surfaces. Additional experience in one or more of the following areas would be highly desirable:o Statistical analysis methods, including use of MiniTab.o Methods for characterizing ligand-protein interactions (binding kinetics, binding affinity).o Automation of the assay workflow.o Surface functionalisation, purification and characterisation of nanoparticles.o Fluorescence-based biochemical techniques (e.g. microarray, cell labelling, gel electrophoresis, flow cytometry).o Programming for automation of data analysis.Salary circa £36k per annum but flexible for the right candidate.To apply for this Fluorescence Assay Development Researcher role in Cambridgeshire please contact us ASAP!