Global Clinical Product Lead Early Late Phase Onc

Job Description

Global Project LeadAstraZeneca is one of the world’s leading pharmaceutical companies, with strong positions in many therapeutic areas of the global pharmaceutical market. At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. AstraZeneca’s Research & Development is based in a number ofcentresof excellence with state-of-the-art facilities in Sweden, United Kingdom and North America, including an important site in Waltham, MA.This opportunity is available at our Gaithersburg, New York City, Boston, South San Francisco, or Cambridge, UK locations.At AstraZeneca, we are committed to advancing the science of oncology to deliver life-changing medicines to patients most in need. With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death. We currently have nearly 100 Phase 1, 2, 3 and Lifecycle Management Oncology projects in our robust pipeline. We deliver the Research & Development for Oncology through our Oncology R&D Unit. This unit has responsibility for the value chain from discovery through to late-stage development, enabling rapid acceleration of promising early-stage assets and life-cycle management programs.Overview:The Hematology Research and Early Development (R&D) team has the accountability for all drug development activities in hematology research from first in man studies, all the way to late-stage trials leading to drug approval by regulatory agencies (Phase 1, 2 and 3 trials). The team aims to deliver compelling preclinical, clinical and translational data packages providing confidence in the dosing strategy, tolerability profile and therapeutic efficacy of our candidate drugs to support investment in late stage clinical development, leading to drug approval.We are looking for a highly qualified candidate to lead the development and execution of the product strategy for one or more projects. This individual will be accountable for the strategic leadership and execution and act as the champion for the product candidates. The individual will develop a range of strategic and tactical options, secure governance and budget approval, and secure cross-functional resource for the projects and then take accountability for execution, monitoring and reporting of progress / issues. The individual will articulate the project goals, strategy and the underlying science and clinical need to internal and external audiences with clarity and credibility.In this role the candidate will work with other project leaders, scientific and clinical leaders and external experts to develop integrated project plans which can be delivered across functional boundaries. The candidate will ensure that diverse views within the team are heard and that a strongly empowered and motivated team is created, and will demonstrate highly visible leadership within the oncology community, both within AZ and externally. The successful candidate will have hematology/oncology clinical drug development experience, demonstrated leadership, and be able to critically navigate the science that underlies these programs. The candidate should be able to effectively communicate across a broad range of audiences and have an ability to clearly articulate project specific strategies as well as the overall oncology strategy.Major Duties and Responsibilities: