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Job Location | Royston |
Education | Not Mentioned |
Salary | Competitive salary |
Industry | Not Mentioned |
Functional Area | Not Mentioned |
Job Type | Permanent, full-time |
Statistical Geneticist / Genome Analyst, Centre for Genomics ResearchLocation: CambridgeSalary & Package: Competitive At AstraZeneca, we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality.Discovery SciencesDiscovery Sciences applies deep technical expertise in specialist technologies to support the delivery of targets and molecules to the early AstraZeneca pipeline. Targets are identified through our human genomics and functional genomics efforts, employing the latest technologies in genome editing and sophisticated cell model development. Once identified and validated, we work with therapy area project teams to identify novel small molecules effectors of these targets using our coordinated sample management and platform screening groups.Our Genomics Research CentreAstraZeneca’s Centre for Genomics Research (CGR) has an opportunity for a Statistical Geneticist or Genome Analyst to contribute to its Genomic Initiative. The Genomic Initiative includes the sequencing of participants from AstraZeneca clinical studies as well as analysing the sequence data from large population cohorts, including the 500,000 UK Biobank participants. Genomics is fundamental to our laboratory research, our clinical trials and the launch of new precision medicines. Our in-house clinico-genomic database is already among one of the largest globally, currently housing hundreds of thousands of human exome and genome sequences. These enable AstraZeneca to identify genetic determinants for disease risk, validate new targets for medicines and improve patient stratification opportunities among core areas of oncology, respiratory, cardiovascular, renal and metabolic disease.This role represents an exciting opportunity to be part of ground-breaking research at the forefront of human genomics. Depending on the experience and interests of the job holder, this role will focus either on the development of innovative and robust statistical methods to analyse large-scale human genomics datasets (statistical geneticist), or more on the application of such methods and interpretation and communication of results (genome analyst). Job holders will be part of a dynamic team in CGR’s multidisciplinary genomics research environment comprising bioinformaticians, computational biologists, genome scientists, software engineers, postdoctoral researchers, disease area specialists. The role will also work closely with specialists in translational science, drug discovery, pre-clinical modelling, and clinical development.Responsibilities: