Graduate Associate Scientist - iPSC in-vitro assays

Job Description

Associate Scientist - Cell based assays for drug developmentTEC Partners are recruiting for an exciting Biotech company based in Newcastle, who are aiming to transform drug discovery by developing the best in vitro biology to mimic and predict how new drugs interact with human tissues and organs.The company has unique capabilities in the development and commercialisation of 2-D and 3-D (organoid) in vitro assays, and they work with global pharmaceutical companies to provide important data on the safety, pharmacology and efficacy of new therapies.They are currently focused on four tissue platforms; kidney, retina, liver and lung.They are looking for talented and passionate individuals to work on projects across their Kidney and Lung platforms. You will be working as part of a team on developing complex iPSC derived models.The job is located at modern laboratories close to the centre of the vibrant city of Newcastle upon Tyne, UK.Associate Scientist Responsibilities:-Contributing to the development, optimisation, and validation of robust techniques, protocols and assays for commercial and R&D projects-Carrying out the isolation and maintenance of a range of primary and iPSC derived cells-Responsibility for running relevant assays under the direction of Senior members of the team-Working within and across assay teams to successfully deliver customer specific projects-Accountability for the accurate technical execution of the projects-Ensuring accurate and traceable record keeping in line with company policies and project-specific requirements-Managing the day-to-day operations of the laboratory including stock, equipment and safety documentationAssociate Scientist Profile:Essential:-Scientific graduate with a BSc/MSc in Pharmacology/Biomedical sciences or equivalent subject-Prior experience of mammalian tissue culture-Experienced in molecular biology techniques, including DNA/RNA isolation, PCR, RT-qPCR, Western blotting, flow cytometry, immunohistochemistry, fluorescent microscopy-Experience in IT and statistical analysis-Demonstrate ability to efficiently learn new laboratory techniques and ability to prioritise a varied workload-Excellent organisational skills including maintenance of accurate and traceable records-Track-record of contributing in a team environment-Good verbal and written communication skillsDesirable (these are across 2 roles, so please do not worry if you dont have many!):-Previous experience in lung physiology/disease and/or epithelial cell biology-Previous experience in the culture and/or differentiation of pluripotent stem cells-Previous experience in co-culture systems-Industrial experience and training in a similar role of developing and running cell-based assays-Experience in handling human tissue-Background in drug development/ADMET-Experience of in vitro toxicology-Prior experience in GLP and SOP-Prior experience in COSHH and risk assessment preparationCompany values:

• Solving challenging problems that make a difference
• Transparency and honest communication
• Valuing and harnessing diversity
• Scientific excellence and rigour
• Well-being and personal growth

In return, they are offering:

• Full time, permanent position
• A competitive starting salary, with participation in a bonus scheme
• Pension
• Flexible working policy and 25 days holiday per annum on top of bank holidays
• Personal development opportunities including training and publication
• Company events
• Cycle to work scheme
• Free coffee