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Senior Scientist - Translational R&D

Next Phase Recruitment
Job LocationLondon
EducationNot Mentioned
Salary50,000 - 60,000 per annum
IndustryNot Mentioned
Functional AreaNot Mentioned
Job TypePermanent , full-time

Job Description

A clinical stage Cell Therapy company who are at the cutting edge of research because of their unique T Cell technology for the regulation of the immune system. They have an expanding pipeline of therapies moving to clinical trials and under developmentat the translational & discovery stages. Their longer term ambition is to be a global biopharmaceutical company to deliver innovative & life changing therapies to patients. They are seeking a Data Scientist to join their West London base to accelerate thedevelopment of the next generation of therapies for autoimmune and inflammatory diseases.The Senior Scientist will be a key role within their expanding Translational team by leading the characterisation of the T Cell product. This includes studying the immune landscape patients for new therapeutic targets and qualifying the experimental programmesto support clinical trials. As a Senior Scientist you will be responsible for managing a small team of up to 5 scientists and research associates. You will be working on a number of projects at a time in collaboration with colleagues in other areas of thecompany. Presenting findings and results regularly to colleagues and the leadership team of the company.The core responsibilities are:

  • Manage, mentor and guide a team of Scientists and Research Associates.
  • Generate and test engineered human immune cells using their proprietary platform.
  • Design, Develop and run cell based assays to evaluate the immune cell function.
  • Design in vitro studies using primary or immortalised immune cells.
  • Perform the characterisation of immune cells using multi colour flow cytometry.
  • Manage projects in collaboration with other departments.
  • Manage external collaborations as an SME in immunology.
Key Experience Required:
  • PhD in a relevant area such as immunology, molecular biology, cell biology etc.
  • Expertise of T cell Immunoassay development
  • Characterisation of immune cell populations using flow cytometry and molecular biology tools
  • Prior expertise of supervisory or management experience
  • Knowledge of T cell immunology
  • Expertise in the culture of primary human cells
Company Overview:The company have developed unique TCell technologies that are innovative and life changing for patients that suffer from autoimmune and inflammatory diseases. As well as having the potential to prevent the rejection of new organs following transplant.This technology is based on modular, engineered Tregs.They are engineering TCells ex vivo that suppress the immune system and have the ability to direct the cells to the right area of the body. They are now expanding their operations as their cell therapies progress to clinical trials, develop their pipelinefurther and develop manufacturing operations for Phase I trials.As a company they are led by some of the leading minds in their field are driven and committed to the development of therapies that are life changing to patients. With the vision to develop a global biopharmaceutical company that is bringing cell therapiesfor a range of diseases beyond their current pipeline.

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