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Lead Bioinformatician - Vaccines

Job LocationLondon
EducationNot Mentioned
Salary60,000 - 75,000 per annum
IndustryNot Mentioned
Functional AreaNot Mentioned
Job TypePermanent , full-time

Job Description

Data science & bioinformatics for drug discovery. Python, NGS, biotech London - home based, antigen, vaccine Your new companyOff the back of a significant seed funding round, this exciting and innovative biotech are increasing their team to help develop the next generation of universal vaccines. Theyre hiring multiple positions as they move their portfolio through preclinical discoveryand are looking to add two bioinformaticians - one at a senior level and one lead. With world leading scientists helping advise their research, and significant development plans, therell be plenty of opportunities for career progression and development.Your new roleYou will be leading projects related to the discovery and development of new cutting-edge vaccines, primarily through the analysis and interpretation of NGS and other data sets to identify and validate antigens.This is a high-level hands-on role working as part of a cross-functional team, interacting closely with biologists, computer scientists and senior/C-Level stakeholders.The position offers good scope for flexible working. Reporting directly to the CTO and CEO, you will lead projects focused on developing their discovery platform; youll also have a significant chance to feed into the companys research strategies. Youll be a key player in determining how the department shouldgrow and have the potential to take on people management. Major responsibilities will include:

  • Develop and manage bioinformatics pipelines for the analysis of large scale NGS (and other omics) data, using Python
  • Project management and research leadership
  • Modelling pathogen genomics / infection dynamics, eg evolutionary modelling
  • Using advanced computational methods, including Machine Learning, as well as things such as Bayesian inference/MLE
  • Develop / optimise algorithms
  • Help to develop and improve the companys existing discovery platform to identify and design antigens
  • Work closely with cross-functional team members, eg biologists and computer scientists
For more senior / experienced candidates there is significant scope to drive the computational research strategy.What youll need to succeedAs well as strong communication, organisational and time management skills, you should have:
  • An MSc / PhD (or equivalent experience) in a subject such as Bioinformatics, Virology, Computational Biology or similar
  • Strong hands-on programming skills in Python, with other languages such as R or C++ an advantage
  • The ability to work to tight deadlines / in a fast-paced environment
  • A track record of pipeline, tool, model or algorithm development
  • A good understanding of pathogen genomics (eg bacterial or viral), with experience of evolutionary modelling or analysing selection pressures an advantage
Experience with the following is not necessary but would be an advantage:
  • Bayesian inference / using BEAST
  • Computational antigen discovery / development
  • Drug discovery or development within the pharmaceutical / biotech industry
  • Vaccine development
  • Data visualisation
What youll get in returnThe chance to work on a range of cutting edge projects for a really exciting company, as well as the ability to directly influence the discovery and development of vaccines that will make a real difference to patients the world over.Youll be joining the company as they go into their next growth phase, so there will be chances to further develop your skills and career and for more senior people the ability to directly influence research strategy.Theres also the potential for equity in the company.What you need to do nowIf youre interested in this role, click apply now to forward an up-to-date copy of your CV, or call me on .If this job isnt quite right for you but you are looking for a new position, please contact us for a confidential discussion on your career, especially as there are a number of other bioinformatics, data science and statistics positions available.Keywords: bioinformatics, bioinformatician, data, science, statistics, statistical, biomarker, discovery, genetics, genomics, evolution, modelling, vaccine, antigen, viral, pathogen, NGS, PCR, RNA, single, cell, scRNA, sequence, Bayesian, BEAST, MLE, machine,learning, programmer, programming, scientist, diagnostics, molecular, python, R, C, Bash, platform, project, manager, developer, tool, pipeline, computational

Keyskills :
PCRRNABayesianMLENGSsciencedatamachinemodellingstatisticssinglegeneticsbioinformaticsvaccinestatisticalgenomicsevolutiondiscoverycellviralbiomarkerpathogenbioinformaticianscRNABEASTantigensequence

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