| London Jobs |
| Manchester Jobs |
| Liverpool Jobs |
| Nottingham Jobs |
| Birmingham Jobs |
| Cambridge Jobs |
| Glasgow Jobs |
| Bristol Jobs |
| Wales Jobs |
| London Jobs |
| Manchester Jobs |
| Liverpool Jobs |
| Nottingham Jobs |
| Birmingham Jobs |
| Cambridge Jobs |
| Glasgow Jobs |
| Bristol Jobs |
| Wales Jobs |
| Oil & Gas Jobs |
| Banking Jobs |
| Construction Jobs |
| Top Management Jobs |
| IT - Software Jobs |
| Medical Healthcare Jobs |
| Purchase / Logistics Jobs |
| Sales |
| Ajax Jobs |
| Designing Jobs |
| ASP .NET Jobs |
| Java Jobs |
| MySQL Jobs |
| Sap hr Jobs |
| Software Testing Jobs |
| Html Jobs |
| Job Location | Cambridge |
| Education | Not Mentioned |
| Salary | £35,000 - £45,000 per annum |
| Industry | Not Mentioned |
| Functional Area | Not Mentioned |
| Job Type | Contract, full-time |
Project title: Modelling Amyotrophic lateral sclerosis (ALS) in an in vitro human iPSC-based co-culture systemAstex Pharmaceuticals is a world leader in innovative drug discovery and development. The company has successfully applied its proprietary Fragment-Based Drug Discovery (FBDD) platform to generate multiple new drug candidates that are progressing in clinical development. Successful collaborations have led to two launched oncology drugs (Kisqali® partnered with Novartis and BalversaTM partnered with Janssen). Astex continues to grow and focuses on Oncology and Neurological Disorders.Astex’s sustaining innovation Postdoctoral research program aims to maintain and further enhance the Company’s excellent scientific culture by fostering basic research in areas of interest to the drug discovery field, whilst working with scientists in both the biotech sector and with academic.Applications are invited for an exciting postdoctoral opportunity within the Biology Department to advance disease relevant IPSC co-culture models to study neurodegeneration. Focussing on ALS, neuron/microglia co-culture systems will be generated and evaluated with state-of-the-art phenotypic profiling methods to better understand the role of neuroinflammation in neurodegenerative disease. The successful candidate will utilize gene editing and proteomics to investigate repeat expansion driven IPSC ALS models and will have the opportunity to work with bioinformatics in order to explore the biological mechanisms underpinning the disease.Candidate Requirements