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Scientist: Compound Management & Automation

Talentspa
Job LocationCambridge
EducationNot Mentioned
SalaryCompetitive salary
IndustryNot Mentioned
Functional AreaNot Mentioned
Job TypePermanent, full-time

Job Description

Scientist: Compound Management & Automation for Cell-based ScreeningLocation: CambridgeSalary: CompetitiveAbout the Company:Horizon Discovery have an exciting opportunity for a Scientist I to join our screening department in the compound management and automation group to support the expansion of our state-of-the-art compound, CRISPR-Cas9 and RNAi screening platforms. This is varied role where you will be contributing to the management of reagent stocks (compound, CRISPR and siRNA libraries), as well as the running of the screening automation to ensure timely completion of all daily screening runs for client and internal projects.This is a lab-based role and candidates should be highly self-motivated, able to work to tight timelines and be comfortable working under pressure in an environment with shifting prioritiesNote that, where needed, this position will require flexible working to cover evening and 7-day operations.Scientist Responsibilities:

  • Management of Horizon’s Screening Services compound, CRISPR, and siRNA libraries:
  • Cataloging, database and LIMS management
  • Compound and reagent ordering
  • Curation of compound, CRISPR and siRNA stocks
  • Preparation of CRISPR lentiviral libraries
  • Planning and preparation of compound source plates for use in client screening projects
  • Operate, maintain and quality control (QC) testing of high throughput screening production equipment including ECHO acoustic dispensers, Hamilton and Tecan liquid handling robots and robotic arms in a bespoke automated setting
  • Troubleshoot problems with scientific production equipment so that program timelines remain on-track for anticipated data-delivery
  • Monitor and record production run progress, errors and corrective action in accordance with regulatory requirements
  • Contribute to QC of screening data
  • Support the further development of Horizon’s automation and compound management capabilities
    • Scientist Requirements:
  • Degree or diploma in relevant discipline (or equivalent experience)
  • A careful and meticulous nature with exceptional attention to detail
  • Ability to work in a highly dynamic environment and on several different projects or tasks concurrently
  • Ability to work to tight timelines and be able to manage a busy workload
  • Flexible, adaptable, independent, resilient and able to work in a matrix-managed environment
  • Excellent interpersonal and communication skills, both written and verbal
  • Although beneficial, prior laboratory, compound management or automation experience is not required as full training will be provided and we strongly encourage applications from detail-oriented individuals with transferable skills from other fields involving logistics, curation, archiving or cataloguing
    • Desirable:
  • Experience in a cell biology, compound management or automation setting
  • Experience of working in industry
  • Knowledge of lab information management systems (LIMS) and liquid handling robotic equipment (although full training will be provided)
  • Experience of maintaining an organised and accessible inventory of high value materials
  • Experience with inventory management software
  • Writing software scripts
    • If you think that you are suitable for this Scientist: Compound Management & Automation for Cell-based Screening role, please apply now!Horizon Delivers inspired solutions that harness the power of the cell. We are global leaders in cell engineering. Our vision is to unlock the power of the cell, and we are increasing our focus on customers every day. Our unique tools and services are used by our customers to provide valuable insights and applications in - research, drug discovery, molecular diagnostics and biomanufacturing.We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

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