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Oncology Medical Director

GSK
Job LocationBrentford
EducationNot Mentioned
SalaryCompetitive salary
IndustryNot Mentioned
Functional AreaNot Mentioned
Job TypePermanent, full-time

Job Description

Site Name: UK - London - BrentfordPosted Date: Jul 9 2020Oncology Medical Director – Oncology (Grade 5) Company BackgroundGSK Oncology is one of GSK Pharma’s 4 core therapy areas and is considered a future growth driver for the company. In 2014, GSK divested its Oncology late stage development and commercial business (ie targeted therapies such as kinase inhibitors and other traditional anti-cancer agents) to Novartis. However, GSK retained its Oncology discovery/preclinical portfolio (comprised of innovative next generation anti-cancer agents) and infrastructure. Since 2014, GSK has progressed this innovative portfolio and has delivered over 16 novel assets into clinical development (alone or in partnership). Moreover, GSK Oncology has established a strong position and focus in four areas; namely, synthetic lethality, cancer epigenetics, immuno-oncology, and oncology cell therapies (TCR-T and CAR-T).The GSK Oncology vision is to maximise the survival of cancer patients by delivering transformational medicines alone or in combination. In addition to in-house discovery and development, the Therapy Area (TA) will rely on outside innovation to deliver this vision. Importantly, Oncology represents one of the most heavily invested and innovative therapy areas across the life sciences and Healthcare industry. The field is evolving at an unprecedented pace and, if leveraged/accessed properly via business development, is expected to contribute to the overall vision of GSK Oncology.DetailsAs a global healthcare company, GSK takes on some of the world’s biggest healthcare challenges. The biggest contribution we can make to society is to innovate and widen access to new medicines, vaccines and consumer healthcare products. We continue to be committed to develop medicines to support fighting cancer. Over the last few years our R&D team has been using ‘next generation’ technology platforms to increase understanding of disease mechanisms, which will help us deliver significant medical advances to cancer patients.Your role will be at the forefront of GSK’s re-emergence in discovering and providing cutting edge Immuno-Oncology treatments. Our leading Oncology asset is belantamab mafodotin, an anti B-cell maturation agent (BCMA) monoclonal immunoconjugate. This is a first in class antibody drug conjugate that has a four-fold mechanism of action with evidence of high efficacy in Multiple Myeloma patients. BCMA has been granted Breakthrough Therapy Designation from the FDA and EU Prime designation. Other assets such as ICOS for Head & Neck and Lung Cancer, NYESO-1 for synovial sarcoma and other solid tumours, M7824 (bintrafusp) for lunch and biliary tract cancers amongst others in our rich oncology pipeline.PRIMARY RESPONSIBILITIES:

  • The Oncology Medical Director is the single point of medical accountability in the UK for our late stage, first in class pipeline including but not limited to belantamab mafodotin, ICOS, NYESO-1, M7824 (bintrafusp) and others.
  • Aligns and directs all medical affairs resources into a focused vision and strategy for each compound including external expert mapping, medical engagement plans, medical affairs strategic foundation and platform execution, real-world evidence generation, advisory boards, symposia, data generation and dissemination and scientific engagement
  • Works seamlessly with MSL Director to produce best in class field medical plans for each pipeline asset not included in women’s cancer portfolio
  • Provides one medical affairs voice, medical expertise, and insight within country for pipeline assets outside of women’s cancer
  • Collaborates with clinical development and global and regional medical affairs leaders to provide insights and ensure country needs and issues are addressed
  • Incorporates country Medical Affairs voice at the global franchise or business unit level when required and at the monthly Global Medical Affairs Team meetings.
  • Build relationships with key external experts in the UK Oncology community and Patient Advocacy Groups
  • Leads the interpretation, translation and integration of medical voice of customer (patients, providers, payers) into medical affairs strategy and prioritises patient’s benefit and welfare. Supports local execution of UK expanded access programmes
  • Maintains deep product and disease expertise on the medicine(s) and includes market and competitive knowledge in all medical plans.
  • Provides input into the design of Phase IIIB/IV studies and selection of investigator sponsored studies in alignment with the global franchises.
  • Support Country Oncology Head in all Medical Affairs activities and needs as related to pipeline compounds
  • Leverage medical and scientific knowledge to ensure that all materials produced are medically and scientifically accurate and in compliance with local and GSK requirements
  • Lead on training of MSLs and develop MSL materials for use in the field
    • Qualifications and ExperiencePreferred: Medical doctor with Board certification/qualification, and clinical experience in oncology or hematology/oncology preferred.•Scientist with Ph.D., Pharm D or equivalent• Significant pharmaceutical industry and scientific/medical affairs experience is required.• Deep clinical and scientific knowledge in hematological malignancy, immuno-oncology, multiple myeloma preferred• Launch experience is required• The position will require many internal and external senior leadership interactions; including at external national and regional meetings. Local or Global experience in these types of arenas is considered as an asset.• Thorough understanding of the UK healthcare environment, stakeholders and customers.• Demonstrated effectiveness for development and execution of medical strategy.• Excellent communications and leadership skills: able to effectively communicate written and verbal scientific data and to understand the clinical implications of the data.• Experience in line management and leadership of highly effective and motivated matrix teams.• Skilled in leveraging available resources to drive business improvement.• Demonstrated ability of strategic thinking, project management, and leadership/management• Demonstrated ability to work across boundaries and geographies effectivelyBASIC QUALIFICATIONS:
  • MBBS, MD, PhD or PharmD
  • Strong foundation/expertise in the disease and therapeutic area (Oncology)
  • Ability to apply scientific knowledge and lead research programsAbility to manage relationships with internal and external partners including Key External Experts

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